(i) Reaction Mechanism: General methods (both kinetic and non-kinetic) of study of mechanisms of organic reactions: isotopic method, crossover experiment, intermediate trapping, stereochemistry; energy of activation; thermodynamic control and kinetic control of reactions.
(ii) Reaction Intermediates: Generation, geometry, stability and reactions of Carbonium ions and carbanions, free radicals, carbenes, benzynes and nitrenes,
(iii) Substitution Reactions:- -SN1. SN2. And SNi. Mechanisms, neighboring group participation; electrophilic and nucleophilic reaction of aromatic compounds including heterocyclic compounds-pyrrole, furan, thiophene and indole.
(iv) Elimination Reactions:- E1, and E2 and E1 cb mechanisms; orientation in E2 reactions Saytzeff and Hoffmann; pyrolytic syn elimination –acetate pyrolysis, Chugaev and Cope eliminations.
Addition Reaction:- Electrophilic addition to C=C and C≡C nucleophilic addition to C=O, C ≡ N, conjugated olefins and carbonyls.
Reactions and Rearrangements:-
(a) Pinacol-pinacolone, Hoffmann, Beckmann, Baeyer-Villiger, Favorski, Fries, Claisen, Cope, Stevens and Wagner-Meerwein rearrangements.
Aldol condensation, Claisen condensation, Dieckmann. Perkin, Knoevenagel, Witting, Clemmensen, Wolff-Kishner, Cannizzaro and von Richter reactions; Stobbe, benzoin and acyloin condensations; Fischer indole synthesis, Skraup synthesis, Bischler Napieralski, Sandmeyer, Reimer-Tiemann and Reformatsky reactiosns.